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Ibutasterone (MK-677 & 20-Hydroxyecdysone)

Ibutamoren(MK-677)

Molecular formula: C27-H36-N4-O5-S

Molar Mass: 528,662 g/mol

PubChem (CID): 9939050

Purity (HPLC): 98,6%

Ecdysterone (20-Hydroxyecdysone)

Molecular formula: C27-H44-O7

Molar Mass: 480,642 g/mol

PubChem (CID): 5459840

Purity (HPLC): 98,0%

Ibutamoren (laboratory code MK-677, MK-0677) is a non-peptide agonist of ghrelin receptors of a long-term effectiveness that stimulates the secretion of the growth hormone. It is the most potent stimulator of the growth hormone currently and it is being used as a potential method for the treatment of deficit of the growth hormone among children and elderly people.

Ibutamoren strengthens the secretion of the growth hormone and insulin-like growth factor-1, wherein not increasing the cortisol level and enhance lipolyses and is being used for treating obesity and complications associated with it.

Ecdysterone (20-Hydroxyecdysone, 20E) – an androgenic steroid hormone of insects, which has a biological effect on humans: enhances anabolism and protein synthesis, as well as has antitumor, adaptogenic and antioxidant effects.

Ecdysterone does not inhibit the natural production of testosterone and does not affect the level of other hormones. Studies of the drug showed that at a daily dosage of 200 mg, no androgen receptor binding was observed in ecdysterone. To increase muscle mass, the recommended dosage is 5 mg per 1 kg of an athlete’s weight. When the dosage is increased, the quite strongly decrease in fat mass is observed. Toxic effect occurs at high dosages of more than 6 g per 1 kg of the body weight.

Ibutasterone has the following effects on a human body:

  • Increases protein synthesis.
  • Reducee the processes of protein breakdown.
  • Increases the GHRH production.
  • Decreases the level of somatostatin.
  • Increases the IGF-1 level.
  • Accelerates metabolism.
  • Increases the level of free testosterone.

When using Ibutasterone, you can achieve the following goals:

  • Increase in muscle mass.
  • Prevent loss of muscle mass.
  • Reduce adipose tissue.
  • Increase strength.
  • Increase endurance.
  • Repair damaged ligaments.
  • Improve the general condition of the body.

The medicine has a beneficial effect on the body and does not require any recovery measures after its application.

For research purposes only.